| Date | Opponent/Event | Location | Time |
|---|---|---|---|
| 09/05/09 | vs. Northern Iowa | Iowa City, IA | W, 17-16 |
| 09/12/09 | at Iowa State | Ames, IA | W, 35-3 |
| 09/19/09 | vs. Arizona | Iowa City, IA | W, 27-17 |
| 09/26/09 | at Penn State | University Park, PA | W, 21-10 |
| 10/03/09 | vs.Arkansas State | Iowa City, IA | W, 24-21 |
| 10/10/09 | vs. Michigan (HC) | Iowa City, IA | W, 30-28 |
| 10/17/09 | at Wisconsin | Madison, WI | W, 20-10 |
| 10/24/09 | at Michigan State | East Lansing, MI | W, 15-13 |
| 10/31/09 | vs. Indiana | Iowa City, IA | W, 42-24 |
| 11/07/09 | vs. Northwestern (FW) | Iowa City, IA | L, 17-10 |
| 11/14/09 | at Ohio State | Columbus, OH | L, 27-24 (OT) |
| 11/21/09 | vs. Minnesota | Iowa City, IA | W, 12-0 |
| 01/05/10 | vs. Georgia Tech | Miami, FL | W, 24-14 |